Group

As you venture deeper into the wasteland of Fallout 76, reaching the endgame means facing off against some of the toughest enemies and surviving the harshest conditions. Whether you're up against massive mutant bosses or other players in PvP, having the right weaponry can make all the difference. Here are 23 must-have weapons for the endgame that can give you a competitive edge in the post-apocalyptic world of Appalachia.

1. Gauss Rifle

One of the most powerful energy weapons in the game, the Gauss Rifle delivers high damage with a slow rate of fire. Perfect for long-range combat, it's a great choice for picking off enemies from a distance.

2. The Fixer

This stealth-based rifle is perfect for those who like to remain unseen. Its high damage and whisper-quiet shots make it deadly in both PvP and PvE situations.

3. Anti-Armor Plasma Gun

If you're up against enemies with high defense, this weapon is a game-changer. Its ability to ignore armor makes it a great pick for endgame content, where heavy armor is a common defense.

4. Wastelanders' Favorite - Handmade Rifle

An excellent weapon for those who prefer versatility, the Handmade Rifle is customizable and highly effective in mid-range combat. Its fast fire rate ensures you'll be able to handle most threats.

5. Brahmin Skinner

A unique weapon for dealing with pesky critters, the Brahmin Skinner deals massive damage to small and medium enemies, making it ideal for clearing out packs of mole rats or ghouls.

6. Two Shot Explosive Laser Rifle

For those who enjoy causing devastation, the Two Shot Explosive Laser Rifle is a fantastic choice. Its explosive rounds can take out large groups of enemies in a single shot.

7. Deathclaw Gauntlet

This melee weapon is a staple for any player looking to go full beast mode. It deals massive damage and can make quick work of most enemies in close-range combat.

8. Tactical Handmade Rifle

Offering precision with every shot, this tactical rifle is highly effective in endgame content, especially against those tough bosses that require precise shots to take down.

9. Furious Power Fist

Melee lovers will find the Furious Power Fist to be a godsend. It increases in damage as you hit more enemies, making it great for chain-killing multiple opponents.

10. Mutant Slayer's Sword

This weapon's damage is greatly increased against mutants, making it perfect for battles with Super Mutants and other mutated foes commonly found in endgame areas.

11. Grognak's Axe

A classic melee weapon, Grognak's Axe is known for its high damage output and reliability. It's a favorite for those who want to feel like a barbarian while slaying enemies.

12. The Dragon

A rare shotgun that has high damage output and a unique fire-based effect. The Dragon is great for dealing with large, armored targets that require a high level of stopping power.

13. The Unstoppable's Minigun

For pure damage output, the Unstoppable's Minigun is a heavy-hitter. It chews through enemies quickly, making it one of the best choices for crowd control in endgame scenarios.

14. Explosive Gatling Gun

Firing multiple explosive rounds, this weapon is great for dealing with swarms of enemies. It's especially useful for clearing out smaller creatures that overwhelm you with sheer numbers.

15. VATS-Optimized Alien Blaster

With its fast rate of fire and high damage, the VATS-Optimized Alien Blaster is a powerful energy weapon, great for precision shots in VATS mode. If you're looking to obliterate enemies in a few hits, this is your go-to.

16. Black Powder Rifle

A great weapon for those who prefer the old-fashioned approach to combat. It’s slow, but hits like a freight train. Perfect for taking down high-health enemies.

17. Cryolator

This weapon is perfect for freezing your enemies in place, giving you ample time to follow up with another attack. It's great for crowd control in tight situations.

18. Plasma Caster

The Plasma Caster is a unique weapon that shoots plasma grenades, making it a great option for clearing large areas or taking down armored enemies. It's especially useful in both PvP and PvE.

19. Tesla Rifle

A great energy weapon for both close and medium-range combat, the Tesla Rifle can chain lightning between targets, making it effective in dealing with groups of enemies.

20. The Knuckles

For those who love melee combat, The Knuckles are perfect for up-close brawls. They deliver fast, relentless attacks, making them highly effective in tight combat situations.

21. Radium Rifle

A classic weapon for those who like to deal damage over time. Its radiation effect makes it ideal for taking on heavily armored opponents in long fights.

22. Secret Service Pistol

While it may not have the firepower of other weapons, the Secret Service Pistol is known for its accuracy and fast firing rate. It's a great weapon for players who rely on precision and skill.

23. The Baller

This explosive weapon is perfect for clearing out entire groups of enemies at once. The Baller's high damage and explosive radius can turn the tide of a battle in seconds.

Having the right weapon for the job is essential to surviving the endgame of Fallout 76. With so many choices available, finding your perfect loadout will take some experimentation. But once you've equipped one or more of these must-have weapons, you'll be well-prepared for the toughest challenges in the wasteland.

If you’re looking to bolster your inventory, you can always buy Fallout 76 items Xbox One or buy Fallout 76 bottle caps to help get your hands on some of these powerful tools of destruction.

Now, it’s time to gear up and head out into the wasteland—your enemies won’t know what hit them!